Alveolar bone loss induced by high alcohol consumption in rats

Daniela Martins de Souza, Alan de Aquino Silva, Kauê Alberto Pereira, Vitor Sulz Gonsalves, Vinicius Anéas Rodrigues, Claudemir de Carvalho de Carvalho

Abstract


Objective: The aim of the present study was to assess the effect of regular and constant long-term alcohol consumption on the percentage of the remaining periodontal bone support (PBS) and periodontal bone loss (PBL) in adult rats. Material and Methods: Fifty-four (54) rats were divided into 3 groups: Control (daily water intake, n=18) daily alcohol intake (20% ethanol, n=18) and social alcohol intake (20% ethanol 2x a week, n=18). The rats were treated with continuous free-choice access to both ethanol consumption frequencies. They were euthanized after 90 days and their left mandibles were radiographed for PBS measuring. The same left mandibles were defleshed and stained. The PBL was morphometrically assessed by measuring the distance between cement-enamel junction and alveolar bone crest. Results: Did not show difference (p > 0.05) in the amount of consumed alcohol between the social and daily intake groups. Rats also evidenced lower PBS percentage and higher PBL (p<0.05) in both alcohol consumption groups in comparison to the control. Conclusion: The long-term constant and regular same amount alcohol consumption may cause alveolar bone loss and reduce the remaining periodontal bone support in adult rats. Thus, the alveolar bone loss was associated with the amount of consumed alcohol, rather than with periodicity in periodontitis-free rats.

Keywords

Alveolar Bone Loss; Alcoholism; Ethanol; Periodontal Disease; X-ray.

 


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DOI: http://dx.doi.org/10.14295/bds.2017.v20i4.1456